Article
The P2X7 receptor gene polymorphism 1513 A-->C has no effect on clinical prognostic markers, in vitro sensitivity to fludarabine, Bcl-2 family protein expression or survival in B-cell chronic lymphocytic leukaemia.
British journal of haematology - 1 Oct 2003
Starczynski Jane, Pepper Chris, Pratt Guy, Hooper Laura, Thomas Alun, Hoy Terry, Milligan Donald, Bentley Paul, Fegan Christopher
Abstract excerpt
A cohort of 121 patients with B-cell chronic lymphocytic leukaemia (B-CLL) was investigated for a single nucleotide polymorphism in the P2X7 receptor gene (1513 A-->C), and the findings were correlated with clinical prognostic markers, in vitro sensitivity to fludarabine, expression of Bcl-2 fami...
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