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Article

Caspase-3-mediated cleavage of Rad9 during apoptosis.

Oncogene - 25 Sept 2003

Lee Michael W, Hirai Itaru, Wang Hong-Gang

Abstract excerpt

The activation of caspases is a critical event for the execution phase of programmed cell death. Caspases are highly specific in their ability to activate or inhibit many crucial proteins in the cell via cleavage. In this study, we report the identification of several caspase-3-like cleavage sites in the cell-cycle checkpoint protein Rad9. We demonstrate that human Rad9 can be specifically cleaved in cells...

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Identifiers

PMID: 14508514
DOI: 10.1038/sj.onc.1206729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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