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Article

Heterozygous disruption of the alpha1,3-galactosyltransferase gene in cattle.

Transplantation - 27 Sept 2003

Sendai Yutaka, Sawada Tokihiko, Urakawa Manami, Shinkai Yoichi, Kubota Keiichi, Teraoka Satoshi, Hoshi Hiroyoshi, Aoyagi Yoshito

Abstract excerpt

BACKGROUND: Animal cloning techniques have enabled gene disruption in several species. Here, we report the first successful disruption of the alpha1,3-galactosyltransferase (alpha1,3-GT) gene in cattle. METHODS: The alpha1,3-GT gene of the Japanese Black cow (JBC) was used to construct pGT-6, a targeting vector for the bovine alpha1,3-GT gene, and pGT-6 was introduced into the fetal fibroblast cell line JBC906 by...

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Identifiers

PMID: 14508351
DOI: 10.1097/01.TP.0000084300.29416.AD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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