Article
Neuronal and astrocytic responses involving the serotonergic system in human spongiform encephalopathies.
Neuropathology and applied neurobiology - 1 Oct 2003
Fraser E, McDonagh A M, Head M, Bishop M, Ironside J W, Mann D M A
Abstract excerpt
The relationships between the degree of cortical prion protein (PrP) deposition, tissue vacuolation and astrocytosis were studied in the frontal cortex of 27 cases of human spongiform encephalopathy, encompassing 13 cases of sporadic Creutzfeldt-Jakob disease (sCJD), four cases of familial CJD (fCJD) (one owing to E200K mutation, one owing to 144 bp insertion, one owing to P102L mutation and one owing to A117V...
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