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Article

Locoregional alpha-radioimmunotherapy of intraperitoneal tumor cell dissemination using a tumor-specific monoclonal antibody.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2003

Huber Roswitha, Seidl Christof, Schmid Ernst, Seidenschwang Sabine, Becker Karl-Friedrich, Schuhmacher Christoph, Apostolidis Christos, Nikula Tuomo, Kremmer Elisabeth, Schwaiger Markus, Senekowitsch-Schmidtke Reingard

Abstract excerpt

PURPOSE: The locoregional application of tumor-specific antibodies conjugated with highly cytotoxic alpha-emitters is a promising new strategy for therapy of i.p. tumor cell dissemination. Using this approach, an antibody specifically targeting diffuse-type gastric cancer cells was coupled to the high linear energy transfer alpha-emitter (213)Bi for treatment of i.p. tumor cell spread in a nude mouse model....

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PMID: 14506190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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