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Article

Cytogenetic alterations in laryngeal carcinomas.

Archives of otolaryngology--head & neck surgery - 1 Dec 1992

Allegra E, Garozzo A, Grillo A, Catalano G B

Abstract excerpt

The purpose of this study was to determine the most frequent chromosomal abnormalities in laryngeal carcinomas. Biopsy specimens of surgical resections from laryngeal squamous cell carcinomas from 15 patients representing different degrees of histologic differentiation were analyzed in short-term culture. Nine of the 15 tumors were hypodiploid with 41 to 45 chromosomes, and four of the 15 tumors were polyploid...

Topics

Carcinoma, Squamous Cell
Chromosome Deletion
Chromosomes, Human, Pair 3
Humans
Karyotyping
Laryngeal Neoplasms
Middle Aged
Phenotype
Ploidies

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1449692
DOI: 10.1001/archotol.1992.01880120046009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1449692-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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