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Article

The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase.

1 Nov 1992

Abstract excerpt

Chromosomal region 11q23 is frequently rearranged in acute lymphocytic leukemias (ALLs) and in acute myeloid leukemias (AMLs), mostly in reciprocal exchanges with various translocation partners. The most common of these translocations is t(4;11)(q21;q23). It is present in approximately 10% of ALL patients, most frequently in very young children. We have recently cloned a region of chromosome 11, the ALL-1 locus,...

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Identifiers

PMID: 1438235
DOI: 10.1073/pnas.89.21.10464

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The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase.PMID 1438235Read ↗

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