Article
Transformed growth phenotype of mouse mammary epithelium in primary culture induced by specific fetal mesenchymes.
Journal of cellular physiology - 1 Nov 1992
Kanazawa T, Hosick H L
Abstract excerpt
When mesenchyme from fetal mammary or salivary gland is implanted into adult mouse mammary gland, adjacent epithelium responds with intense hyperplasia. The hyperplastic cells are more vulnerable than are non-stimulated cells to transformation in vivo by a chemical carcinogen or by mammary tumor...
Topics
- Animals
- Cell Transformation, Neoplastic
- Culture Techniques
- Cytological Techniques
- Epithelial Cells
- Epithelium
- Fetal Tissue Transplantation
- Mammary Glands, Animal
- Mesoderm
- Mice
- Mice, Inbred BALB C
- Phenotype
- Sepharose
- Stem Cells
- Stromal Cells
- Tetradecanoylphorbol Acetate