Article
Specific cytogenetic abnormalities and k-ras mutation in two new human colorectal-adenoma-derived cell lines.
International journal of cancer - 11 Nov 1992
Williams A C, Harper S J, Marshall C J, Gill R W, Mountford R A, Paraskeva C
Abstract excerpt
Two new human epithelial cell lines from sporadic colorectal adenomas designated S/RR and S/BR are reported. Both cell lines have extended growth capacities in vitro, reaching passages 38 and 40 respectively and show no sign of senescence. S/RR and S/BR cell lines have retained the ability to differentiate in vitro, as shown by mucin production from goblet-like cells. S/BR was derived from a large colonic tubular...
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