Article
Retroviral vector-mediated lymphokine gene transfer into human renal cancer cells.
Cancer research - 15 Nov 1992
Gastl G, Finstad C L, Guarini A, Bosl G, Gilboa E, Bander N H, Gansbacher B
Abstract excerpt
Effective vaccination against cancer, either for prophylaxis or therapy, has been an elusive goal for years. Cytokine gene therapy offers a novel approach to generate immunogenic tumor cell vaccines. To examine the feasibility of cytokine gene transfer into human renal cancer (RC) cells, we introduced the cDNAs for human interleukin-2 (IL-2) or interferon-gamma (IFN-gamma) into various RC cell lines with...
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