Article
Retroviral vector-mediated lymphokine gene transfer into human renal cancer cells.
Cancer research - 15 Nov 1992
Gastl G, Finstad C L, Guarini A, Bosl G, Gilboa E, Bander N H, Gansbacher B
Abstract excerpt
Effective vaccination against cancer, either for prophylaxis or therapy, has been an elusive goal for years. Cytokine gene therapy offers a novel approach to generate immunogenic tumor cell vaccines. To examine the feasibility of cytokine gene transfer into human renal cancer (RC) cells, we intro...
Topics
- Animals
- Antigens, Neoplasm
- Carcinoma, Renal Cell
- Cell Survival
- DNA
- Dose-Response Relationship, Radiation
- Gamma Rays
- Gene Expression
- Genetic Vectors
- Humans
- Interferon-gamma
- Interleukin-2