Article
Apo(a) isoforms predict risk for coronary heart disease. A study in six populations.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Oct 1992
Sandholzer C, Saha N, Kark J D, Rees A, Jaross W, Dieplinger H, Hoppichler F, Boerwinkle E, Utermann G
Abstract excerpt
Elevated concentrations of lipoprotein(a) (Lp[a]) in plasma are associated with premature coronary heart disease (CHD). Lp(a) levels are largely determined by alleles at the hypervariable apolipoprotein(a) (apo[a]) gene locus, but other genetic and environmental factors as well as diseases also affect plasma Lp(a) concentrations. It is therefore unclear whether Lp(a) is a primary genetic risk factor or whether...
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