Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease.

doi:10.1172/JCI115645

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Article

Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease.

The Journal of clinical investigation - 1 Mar 1992

Sandholzer C, Boerwinkle E, Saha N, Tong M C, Utermann G

Abstract excerpt

Elevated lipoprotein(a) (Lp[a]) concentrations are associated with premature coronary heart disease (CHD). In the general population, Lp(a) levels are largely determined by alleles at the hypervariable apolipoprotein(a) (apo[a]) gene locus, but other genetic and environmental factors also affect plasma Lp(a) levels. In addition, Lp(a) has been hypothesized to be an acute phase protein. It is therefore unclear...

Topics

Adolescent
Adult
Aged
Apolipoproteins
China
Cholesterol
Cholesterol, HDL
Coronary Disease
Female
Humans
Lipids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipoproteins

Male

Middle Aged

Phenotype

Risk Factors

Singapore

Source

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Identifiers

PMID: 1541665
DOI: 10.1172/JCI115645
PMCID: PMC442954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1541665-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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