Article
The influenza A virus spliced messenger RNA M mRNA3 is not required for viral replication in tissue culture.
The Journal of general virology - 1 Dec 2008
Jackson David, Lamb Robert A
Abstract excerpt
Influenza A virus genome RNA segment 7 encodes three known mRNAs, two of which, M2 mRNA and M mRNA3, are derived by alternative splicing of the primary collinear mRNA transcript using alternative 5' splice sites. The function of M mRNA3 is currently unknown, therefore we attempted to determine whether it is essential for virus replication. Recombinant viruses unable to produce M mRNA3 and/or M2 mRNA were created...
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