Article
Sensory mother cell division is specifically affected in a Cyclin-A mutant of Drosophila melanogaster.
The EMBO journal - 1 Aug 1992
Ueda R, Togashi S, Takahisa M, Tsurumura S, Mikuni M, Kondo K, Miyake T
Abstract excerpt
Cyclin proteins are one of the important components of the mechanism regulating mitosis in eukaryotic cells. We isolated a Drosophila Cyclin-A mutant in which the progenitor cells of the peripheral nervous system (the sensory mother cells) do not divide properly, causing the loss and other abnormalities of mechanosensory organs in the adult fly. Sequence analysis of the mutant genome reveals that a P element is...
Topics
- Animals
- Animals, Genetically Modified
- Cell Division
- Cloning, Molecular
- Cyclins
- Drosophila melanogaster
- Epidermis
- Gene Expression Regulation
- Microscopy, Electron, Scanning
- Mutagenesis, Insertional