Article
[Genetic aspects of the action of immunosuppressive agents].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1992
Pevnitskiĭ L A, Pisarev V M, Telegin L Iu, Tutel'ian A V
Abstract excerpt
The data were obtained formerly that mice of certain strains essentially differ in the sensitivity to the immunodepressive and antiproliferative action of the alkylating agents (so-called opposite strains: DBA/2--highly sensitive, BALB/c--resistant). It is shown in the present work that with the use of the other non-alkylating immunodepressive agents (cytarabine, cyclosporin A, dexamethasone) that differ in the...
Topics
- Alkylating Agents
- Animals
- Antibody-Producing Cells
- Cells, Cultured
- Drug Resistance
- Drug Tolerance
- Genotype
- Immunosuppressive Agents
- Male
- Mice
- Mice, Inbred BALB C
