Article
Recombinant acellular pertussis vaccine--from the laboratory to the clinic: improving the quality of the immune response.
FEMS microbiology immunology - 1 Oct 1992
Rappuoli R, Pizza M, Covacci A, Bartoloni A, Nencioni L, Podda A, De Magistris M T
Abstract excerpt
Vaccination is the most effective way to prevent infectious diseases. Recombinant DNA technologies have provided powerful new tools to develop vaccines that were previously impossible or difficult to make, and to improve the vaccines that were already available but had been developed using old te...
Topics
- Amino Acid Sequence
- Animals
- Bordetella pertussis
- Cloning, Molecular
- Cricetinae
- Epitopes
- Humans
- Molecular Sequence Data
- Mutation
- Pertussis Toxin
- Pertussis Vaccine
- Vaccines, Synthetic
- Virulence Factors, Bordetella
- Whooping Cough