CD34+ marrow cells, devoid of T and B lymphocytes, reconstitute stable lymphopoiesis and myelopoiesis in lethally irradiated allogeneic baboons.

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Article

CD34+ marrow cells, devoid of T and B lymphocytes, reconstitute stable lymphopoiesis and myelopoiesis in lethally irradiated allogeneic baboons.

Blood - 1 Oct 1992

Andrews R G, Bryant E M, Bartelmez S H, Muirhead D Y, Knitter G H, Bensinger W, Strong D M, Bernstein I D

Abstract excerpt

CD34+ cells devoid of detectable mature and immature T and B lymphocytes, expressing the CD2, CD10, and CD20 antigens, were isolated from marrows of three pairs of sex-mismatched, mixed lymphocyte culture (MLC) nonreactive, sibling baboons. Reciprocal transplants were performed between members of each pair, using the sex chromosomes, identified by standard cytogenetic techniques, as markers of the transplanted...

Topics

Animals
Antigens, CD
Antigens, CD20
Antigens, CD34
Antigens, Differentiation
Antigens, Differentiation, B-Lymphocyte
Antigens, Differentiation, T-Lymphocyte
Bone Marrow
Bone Marrow Transplantation
CD2 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hematopoietic Stem Cells

Leukocyte Count

Lymphocyte Culture Test, Mixed

Neprilysin

Papio

Phenotype

Receptors, Immunologic

Transplantation, Homologous

Source

Open in PubMed

Identifiers

PMID: 1382700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1382700-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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