Article
In utero bone marrow transplantation of fetal baboons with mismatched adult baboon marrow.
Blood cells - 1 Jan 1991
Roodman G D, Kuehl T J, Vandeberg J L, Muirhead D Y
Abstract excerpt
In utero bone marrow transplantation to fetuses offers the potential advantage of ameliorating the effects of genetic disorders by transplanting allogeneic hematopoietic stem cells into recipients who are immunoincompetent and require no preparative regimen. Therefore, we undertook studies to examine the feasibility of in utero bone marrow transplantation of unrelated allogeneic adult bone marrow into fetal...
Topics
- Alleles
- Animals
- Animals, Newborn
- Bone Marrow Transplantation
- Chimera
- Female
- Fetus
- Gestational Age
- Glucose-6-Phosphate Isomerase
- Graft Survival
- Isoenzymes
- Lymphocyte Culture Test, Mixed
