Article
Normal immunologic response to a neoantigen, bacteriophage phiX-174, in baboons with long-term lymphohematopoietic reconstitution from highly purified CD34+ Lin- allogeneic marrow cells.
Blood - 15 Aug 1997
Andrews R G, Winkler A, Potter J, Bryant E, Knitter G H, Bernstein I D, Ochs H D
Abstract excerpt
The CD34 antigen is thought to be expressed by hematopoietic stem cells in adult humans and nonhuman primates. We present data that baboons transplanted with highly purified allogeneic CD34+ marrow cells devoid of detectable mature and immature T and B lymphocytes and myeloid cells, isolated from...
Topics
- Animals
- Antibodies, Viral
- Antigens, CD34
- Antigens, Viral
- B-Lymphocytes
- Bacteriophage phi X 174
- Bone Marrow Transplantation
- Female
- Hematopoiesis
- Male
- Papio
- Phenotype
- Polymerase Chain Reaction
- T-Lymphocytes