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Article

Transcriptional Regulation of the Fetal Cardiac Gene Program

1 Jan 2012

Abstract excerpt

Reactivation of the fetal cardiac gene program in adults is a reliable marker of cardiac hypertrophy and heart failure. Normally, genes within this group are expressed in the fetal ventricles during development, but are silent after birth. However, their expression is re-induced in the ventricular myocardium in response to various cardiovascular diseases, and potentially plays an important role in the...

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PMID: 22786561
DOI: 10.1254/jphs.12r04cp

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