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Article

A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity.

Biophysical journal - 1 Apr 1992

Goldstein S A, Miller C

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1376173
DOI: 10.1016/S0006-3495(92)81760-5
PMCID: PMC1260466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity.PMID 1376173Read ↗

Differences in gating among amino-terminal variants of Shaker potassium channels.Semantic proximity Read ↗

Residue Phe266 in S5-S6 loop is not critical for Charybdotoxin binding to Ca2+-activated K+ (mSlo1) channels.Semantic proximity Read ↗

S4 mutations alter the single-channel gating kinetics of Shaker K+ channels.Semantic proximity Read ↗

Mutations in the K+ channel signature sequence.Semantic proximity Read ↗

Reciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.Semantic proximity Read ↗

Genetic modification of potassium channels in Drosophila Shaker mutants.Semantic proximity Read ↗

Effects on ion permeation with hydrophobic substitutions at a residue in Shaker S6 that interacts with a signature sequence amino acid.Semantic proximity Read ↗

Mapping hydrophobic residues of the interaction surface of charybdotoxin.Semantic proximity Read ↗

Hydrophobic substitution mutations in the S4 sequence alter voltage-dependent gating in Shaker K+ channels.Semantic proximity Read ↗

Shaker IR T449 mutants separate C- from U-type inactivation.Semantic proximity Read ↗

R1 in the Shaker S4 occupies the gating charge transfer center in the resting state.Semantic proximity Read ↗

Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges.Semantic proximity Read ↗

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