Article
Developmental appearance, antigenic profile, and proliferation of glial cells of the human embryonic spinal cord: an immunocytochemical study using dissociated cultured cells.
Glia - 1 Jan 1992
Aloisi F, Giampaolo A, Russo G, Peschle C, Levi G
Abstract excerpt
We have investigated the time of appearance of the earliest differentiating glial cell types of human spinal cord using a panel of antigenic markers to identify them in cultures from 6- to 9-week-old human embryos. Immunolabeling performed at 14 h in vitro with the O4 mAb, an early oligodendrocyte marker, showed the presence of oligodendrocytes during the 7th week of age. At 8 weeks only a few of the O4+ cells...
Topics
- Antibodies
- Astrocytes
- Autoradiography
- Cell Division
- Cells, Cultured
- Female
- Glial Fibrillary Acidic Protein
- Humans
- Immunohistochemistry
- Neuroglia
- Oligodendroglia