Article
A clonal analysis of glial lineages in neonatal forebrain development in vitro.
Neuron - 1 Sept 1990
Vaysse P J, Goldman J E
Abstract excerpt
Retrovirus-mediated gene transfer combined with triple immunostaining for astro- and oligodendroglial markers (antibodies to glial fibrillary acidic protein, GD3 ganglioside, and galactocerebroside, and the O4 antibody) was used to study clonal aspects of glial lineage in primary cultures of the neonatal rat striatum. We found two major clonal populations: astrocyte clones containing GFAP+, but GD3-, O4-, and GC-...
Topics
- Animals
- Animals, Newborn
- Cell Line
- Cells, Cultured
- Corpus Striatum
- Fluorescent Antibody Technique
- Galactosides
- Galactosylceramides
- Gangliosides
- Indoles
- Neuroglia
- Phenotype