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Article

Bone marrow-derived stromal cells prevent apoptotic cell death in B- lineage acute lymphoblastic leukemia

1 May 1992

Abstract excerpt

Establishing requirements for the survival of human immature B cells in vitro has proved elusive. In this article, we report prolonged survival of B-lineage leukemic cells on 'feeder layers' of bone marrow (BM)-derived stromal cells in a serum-free environment. In 15 of 18 cases of B-lineage acute lymphoblastic leukemia (ALL), there was a greater than 50% decrease in the number of viable cells after 72 hours of...

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Identifiers

PMID: 1373973
DOI: 10.1182/blood.v79.9.2370.2370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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