Article
Adhesion-dependent survival of normal and leukemic human B lymphoblasts on bone marrow stromal cells
1 Feb 1994
Abstract excerpt
We investigated the requirement for intimate contact between bone marrow stroma and B lymphoblasts from normal donors and children with leukemia. By scanning electron microscopy, both normal and leukemic cells seeded onto stroma were surrounded by folds of stromal cells or were linked to the stroma by fine tendrils and uropods. Separation of normal B progenitors from stroma by use of microporous membranes led to...
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