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Article

Biochemical and molecular genetic analyses on placental aromatase (P-450AROM) deficiency.

1 Mar 1992

Abstract excerpt

Biochemical and molecular genetic studies were made on a case of placental aromatase (P-450AROM) deficiency. Of the enzymes participating in the electron transport system of placental microsomes, only aromatase activity was decreased specifically in the patient, being less than 0.3% of the normal activity. Northern and Western blotting analyses showed that the transcription of the aromatase gene and the...

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PMID: 1371509
DOI: 10.1016/s0021-9258(18)42900-6

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Biochemical and molecular genetic analyses on placental aromatase (P-450AROM) deficiency.PMID 1371509Read ↗

Genetic studies to characterize the origin of the mutation in placental aromatase deficiency.Semantic proximity Read ↗

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Female pseudohermaphroditism associated with a novel homozygous G-to-A (V370-to-M) substitution in the P-450 aromatase gene.Semantic proximity Read ↗

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