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Article

Genetic and clinical spectrum of aromatase deficiency in infancy, childhood and adolescence.

Hormone research - 1 Jan 2009

Belgorosky A, Guercio G, Pepe C, Saraco N, Rivarola M A

Abstract excerpt

INTRODUCTION: cP450aromatase deficiency provides clues for the understanding of the role of aromatase in prepubertal and pubertal human health and disease. Placental aromatization of androgens protects the female fetus against the virilizing action of fetal androgens. After birth, the dual effect of aromatase deficiency, excessive androgens, and insufficient estrogens is responsible for a variable clinical...

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Identifiers

PMID: 19844120
DOI: 10.1159/000249159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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