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Aromatase expression and role of estrogens in male gonad : a review

11 Apr 2003

Abstract excerpt

The ability of the testis to convert irreversibly androgens into estrogens is related to the presence of a microsomal enzymatic complex named aromatase, which is composed of a specific glycoprotein, the cytochrome P450 aromatase (P450arom) and an ubiquitous reductase. The aromatase gene is unique in humans and contained 18 exons, 9 of them being translated. In the rat testis we have immunolocalized the P450arom...

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PMID: 12747806
DOI: 10.1186/1477-7827-1-35

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