Regulation of annexin I in adipogenesis: cAMP-independent action of methylisobutylxanthine.

doi:10.1152/ajpcell.1992.262.1.C91

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Article

Regulation of annexin I in adipogenesis: cAMP-independent action of methylisobutylxanthine.

The American journal of physiology - 1 Jan 1992

Wong W T, Nick H S, Frost S C

Abstract excerpt

The differentiation of 3T3-L1 fibroblasts to adipocytes can be accelerated by the addition of 1-methyl-3-isobutylxanthine (MIX), insulin, and dexamethasone to the culture medium. During differentiation, we have demonstrated that the level of both annexin I mRNA and protein decreases. The half-tim...

Topics

1-Methyl-3-isobutylxanthine
3T3 Cells
Adipose Tissue
Animals
Annexins
Calcium-Binding Proteins
Cell Differentiation
Cyclic AMP
Dexamethasone
Fibroblasts
Insulin
Mice
Phenotype
RNA, Messenger
Time Factors

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