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Article

Gelatinase B (MMP-9) gene silencing does not affect murine preadipocyte differentiation

5 Nov 2013

Abstract excerpt

Growth of adipose tissue involves differentiation of preadipocytes into mature lipid-containing adipocytes. The matrix metalloproteinases (MMPs) are known regulators of adipose tissue biology, and previous studies suggested a key role for gelatinase B (MMP-9) in adipogenesis. In the present study we have evaluated a potential functional role of MMP-9 by performing gene silencing in 3T3-F442A preadipocytes. At the...

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PMID: 24575369
DOI: 10.4161/adip.26966

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