Article
Decreased accessory cell function and costimulatory activity by 1,25-dihydroxyvitamin D3-treated monocytes.
Arthritis and rheumatism - 1 Jan 1992
Rigby W F, Waugh M G
Abstract excerpt
To characterize the mechanism(s) by which 1,25-dihydroxyvitamin D3 (calcitriol) modulates the costimulatory capacity of monocytes, we examined the effect of calcitriol pretreatment of monocytes on their capacity to promote T cell proliferation (accessory cell function). Correlation of calcitriol-...
Topics
- Antigen-Presenting Cells
- Antigens, CD
- CD58 Antigens
- Calcitriol
- Cell Adhesion Molecules
- Cell Division
- Cell Survival
- Cells, Cultured
- HLA-DR Antigens
- Histocompatibility Antigens Class II
- Humans
- Intercellular Adhesion Molecule-1
- Interferon-gamma
- Interleukin-1
- Interleukin-6
- Lectins
- Lymphocyte Activation
- Lymphocyte Function-Associated Antigen-1