DNA-analysis of patients with autosomal dominant polycystic kidney disease.

Article

DNA-analysis of patients with autosomal dominant polycystic kidney disease.

Folia medica - 1 Jan 1992

Dimitrakov D, Kalaidzhieva L, Bogdanov N, Dragova D

Abstract excerpt

Indirect DNA analysis was performed on 12 families totalling 80 people. The analysis used five genetic markers flanking the gene: 3'HVR, pGGG, 218 EP6, 24-1, 26-6. In 11 of the families (92%), a linkage with the PKD1 gene in chromosome 16 was established. In one family, the disease did not segreg...

Topics

Adolescent
Adult
Child
Chromosome Mapping
Chromosomes, Human, Pair 16
DNA
Female
Genetic Linkage
Genetic Markers
Humans
Male
Middle Aged
Mutation
Pedigree
Polycystic Kidney, Autosomal Dominant

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