Article
Prenatal diagnosis of autosomal dominant polycystic kidney disease using flanking DNA markers and the polymerase chain reaction.
Prenatal diagnosis - 1 Jun 1992
Turco A, Peissel B, Quaia P, Morandi R, Bovicelli L, Pignatti P F
Abstract excerpt
A prenatal diagnosis was carried out on a 9-week-old fetus at risk for autosomal dominant polycystic kidney disease (ADPKD). Ten members of the family were previously typed using five DNA markers linked to the PKD1 locus on chromosome 16, and one marker linked to the putative PKD2 locus on chromo...
Topics
- Alleles
- Chorionic Villi Sampling
- Female
- Genetic Markers
- Humans
- Lod Score
- Pedigree
- Polycystic Kidney, Autosomal Dominant
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Pregnancy
- Prenatal Diagnosis