Article
[Indirect genotype analysis in 2 families with early manifestation of autosome dominant polycystic nephropathy].
Klinische Padiatrie - 1 Jan 2000
Schuster V, Uhlhaas S, Horwitz A E, Zerres K
Abstract excerpt
Autosomal dominant polycystic kidney disease (ADPKD) is one of the commonest dominantly inherited disease with an estimated incidence of 1 in 1000. In the majority of cases the ADPKD gene locus is linked to chromosome 16p13.3-markers (PKD1). It has been estimated that approximately 2 percent of P...
Topics
- Child, Preschool
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 16
- Female
- Genes, Dominant
- Genetic Carrier Screening
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Hypertension, Renal
- Infant
- Infant, Newborn
- Male
- Pedigree
- Polycystic Kidney Diseases