[Autosomal dominant hereditary polycystic kidney disease].

Abstract excerpt

BACKGROUND: Molecular genetics are a fundamental turning point in the approach to autosomal dominant hereditary renal polycystosis of adults (ADPKD). DNA analysis makes diagnosis possible at in any ontogenic period, i.e. also during the prenatal period. The objective of the present study was to test the presymptomatic DNA diagnosis in a major group of patients with ADPKD and the possibility to detect the disease...

Topics

• Adult
• Chromosomes, Human, Pair 16
• Female
• Genetic Linkage
• Genetic Markers
• Humans
• Mutation
• Polycystic Kidney, Autosomal Dominant
• Polymorphism, Restriction Fragment Length
• Pregnancy
• Prenatal Diagnosis