Article
p53 alterations and their relationship to SDHD mutations in parasympathetic paragangliomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2003
van Nederveen Francien H, Dannenberg Hilde, Sleddens Hein F B M, de Krijger Ronald R, Dinjens Winand N M
Abstract excerpt
Experimental and observational evidence suggests that chronic hypoxic stimulation can induce parasympathetic paraganglioma. This is emphasized by the identification of germline mutations in genes of the mitochondrial succinate dehydrogenase enzyme complex II in hereditary paraganglioma. Because o...
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