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Article

A novel G106D alteration of the SDHD gene in a pedigree with familial paraganglioma.

American journal of medical genetics. Part A - 15 Nov 2006

Ogawa Kazumi, Shiga Kiyoto, Saijo Shigeru, Ogawa Takenori, Kimura Noriko, Horii Akira

Abstract excerpt

Head and neck paragangliomas are tumors derived from parasympathetic paraganglia. Familial cases account for 10% or more of these tumors, and mutations of the genes encoding subunits for the mitochondrial respiratory chain complex II, SDHD, SDHB, and SDHC, have been reported. We analyzed mutations in the all four SDH genes, SDHA through SDHD, in a Japanese family with cervical paraganglioma that include a father...

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Share to DNA, Neoplasm
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

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Share to Succinate Dehydrogenase

Share to Suppression, Genetic

Source

Identifiers

PMID: 17041923
DOI: 10.1002/ajmg.a.31444

Genes

SDHD
SDHA
SDHB
SDHC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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