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Article

Chromosome 11 monosomy in conjunction with a mutated SDHD initiation codon in nonfamilial paraganglioma cases.

Cancer genetics and cytogenetics - 15 Apr 2004

Riemann Kathrin, Sotlar Karl, Kupka Susan, Braun Simone, Zenner Hans-Peter, Preyer Serena, Pfister Markus, Pusch Carsten M, Blin Nikolaus

Abstract excerpt

Paragangliomas of the head and neck region are a group of rare, usually benign, slow-growing tumors developing from paraganglionic chemoreceptors in most patients. Mutations in a subunit of the mitochondrial enzyme II complex (succinate dehydrogenase [SDHD]) were shown to be responsible for the formation of paragangliomas. In addition, loss of heterozygosity (LOH) on chromosome 11, mainly in 11q23 (PGL1), was...

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Source

Identifiers

PMID: 15066320
DOI: 10.1016/j.cancergencyto.2003.10.013

Genes

SDHD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Chromosome 11 monosomy in conjunction with a mutated SDHD initiation codon in nonfamilial paraganglioma cases.PMID 15066320Read ↗

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