Article
Reverse genetics of Caenorhabditis elegans.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Sept 1992
Plasterk R H
Abstract excerpt
It is somewhat ironic that animals that are the prime choice for detailed genetic analysis, such as the fruit fly and the nematode, have thus far been largely refractory to reverse genetic analysis. Their detailed genetic map, and small genome size have made them subjects of ambitious genome analysis projects, but there is still no strategy to introduce desired changes into their genomes by homologous...
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