Article
Association of HincII RFLP of low density lipoprotein receptor gene with obesity in essential hypertensives.
Clinical genetics - 1 Mar 1995
Zee R Y, Schrader A P, Robinson B G, Griffiths L R, Morris B J
Abstract excerpt
Obese (BMI > or = 26 kg/m2; n = 51) and lean (BMI < 26 kg/m2; n = 61) Caucasian patients with severe, familial essential hypertension, were compared with respect to genotype and allele frequencies of a HincII RFLP of the low density lipoprotein receptor gene (LDLR). A similar analysis was perform...
Topics
- Alleles
- Body Weight
- Cholesterol
- Deoxyribonucleases, Type II Site-Specific
- Female
- Genotype
- Heterozygote
- Homozygote
- Humans
- Hypertension
- Linkage Disequilibrium
- Male
- Middle Aged
- Obesity
- Phenotype
- Point Mutation
- Polymorphism, Restriction Fragment Length
- Receptors, LDL