Article
Association of HincII RFLP of low density lipoprotein receptor gene with obesity in essential hypertensives.
Clinical genetics - 1 Mar 1995
Zee R Y, Schrader A P, Robinson B G, Griffiths L R, Morris B J
Abstract excerpt
Obese (BMI > or = 26 kg/m2; n = 51) and lean (BMI < 26 kg/m2; n = 61) Caucasian patients with severe, familial essential hypertension, were compared with respect to genotype and allele frequencies of a HincII RFLP of the low density lipoprotein receptor gene (LDLR). A similar analysis was performed in obese (n = 28) and lean (n = 68) normotensives. A significant association of the C allele of the T-->C variant...
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