Article
Differential collagen and fibronectin production by Thy 1+ and Thy 1- lung fibroblast subpopulations.
The American journal of physiology - 1 Aug 1992
Derdak S, Penney D P, Keng P, Felch M E, Brown D, Phipps R P
Abstract excerpt
Pulmonary fibrosis resulting from diverse etiologies is characterized by proliferation of fibroblasts and excessive accumulation of interstitial collagen. Whether fibrosis is associated with selective expansion of fibroblast subpopulations differing in amounts or types of collagens synthesized is unknown. We have previously isolated lines and clones of normal murine lung fibroblasts based on the presence of the...
Topics
- Animals
- Antigens, Surface
- Collagen
- Fibroblasts
- Fibronectins
- Lung
- Membrane Glycoproteins
- Phenotype
- Protein Biosynthesis
- RNA, Messenger
- Thy-1 Antigens