The role of amyloid beta-protein in Alzheimer's disease.

doi:10.1016/0140-6736(92)91780-c

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Article

The role of amyloid beta-protein in Alzheimer's disease.

Lancet (London, England) - 22 Aug 1992

Regland B, Gottfries C G

Abstract excerpt

Deposition of amyloid beta-protein in the brain has been regarded as the central event in Alzheimer's disease; however, amyloid beta-protein precursor is an endogenous protein, probably with neurotrophic functions. An alternative hypothesis is that amyloid beta-protein is involved in the disease...

Topics

Alzheimer Disease
Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Animals
Disease Models, Animal
Down Syndrome
Genetic Markers
Humans
Mice
Phenotype

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