Application of cladistics to the analysis of genotype-phenotype relationships.

Abstract excerpt

We seek to understand the relative contribution of allelic variations of a particular gene to the determination of an individual's risk of atherosclerosis or hypertension. Work in progress is focusing on the identification and characterization of mutations in candidate genes that are known to be involved in determining the phenotypic expression of intermediate biochemical and physiological traits that are in the...

Topics

• Alleles
• Animals
• Arteriosclerosis
• Classification
• Drosophila melanogaster
• Gene Expression
• Genotype
• Haploidy
• Humans
• Hypertension
• Models, Genetic
• Mutation