Article
CD8 lymphocytosis and pseudotumoral splenomegaly in HIV infection.
Lancet (London, England) - 25 Jul 1992
Oksenhendler E, Autran B, Gorochov G, D'Agay M F, Seligmann M, Clauvel J P
Abstract excerpt
Three patients infected with human immunodeficiency virus (HIV) presented with pseudotumoral splenomegaly, CD8 lymphocytosis (3.5-5.1 x 10(9)/l), and hypergammaglobulinaemia. Spleen and bone marrow showed diffuse CD8 lymphocyte and plasma-cell infiltration. Amplification of the T-cell-receptor gamma chain gene did not reveal any clonal T-cell population. Phenotypic analysis showed a predominance of CD8/CD57...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- CD8 Antigens
- Female
- Homosexuality
- Humans
- Immunity, Cellular
- Lymphocytosis
- Male
- Opportunistic Infections
- Phenotype
- Splenomegaly