Recalcitrant pseudotumoral anogenital herpes simplex virus type 2 in HIV-infected patients: evidence for predominant B-lymphoplasmocytic infiltration and immunomodulators as effective therapeutic strategy.

doi:10.1093/cid/cit592

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Article

Recalcitrant pseudotumoral anogenital herpes simplex virus type 2 in HIV-infected patients: evidence for predominant B-lymphoplasmocytic infiltration and immunomodulators as effective therapeutic strategy.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Dec 2013

Sbidian Emilie, Battistella Maxime, Legoff Jérome, Lafaurie Matthieu, Bézier Maud, Agbalika Félix, Simon François, Bouscarat Fabrice, Cayuela Jean-Michel, Carcelain Guislaine, Houhou Nadira, Bagot Martine, Molina Jean Michel, Janier Michel, Bachelez Hervé

Abstract excerpt

BACKGROUND: In patients with human immunodeficiency virus (HIV) infection, genital herpetic lesions may be extensive and tend to persist for longer periods; in addition, atypical hypertrophic, ulcerative, or pseudotumor forms have been reported, frequently showing resistance to acyclovir (ACV) treatment. METHODS: Between 2003 and 2011, 10 HIV-1-infected patients presenting with chronic pseudotumoral anogenital...

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PMID: 24065320
DOI: 10.1093/cid/cit592

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