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Article

Formation of a hyperdiploid karyotype in childhood acute lymphoblastic leukemia [see comments]

1 Jul 1992

Abstract excerpt

Hyperdiploidy with greater than or equal to 50 chromosomes is a frequent and distinct karyotypic pattern in the malignant cells of children with acute lymphoblastic leukemia. To understand better the mechanism of formation of the hyperdiploid karyotype, we studied 15 patients using 20 DNA probes that detect restriction fragment length polymorphisms. We first examined disomic chromosomes for loss of...

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Identifiers

PMID: 1351763
DOI: 10.1182/blood.v80.1.203.bloodjournal801203

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Source receipt: pubmed, retrieved 7 Sept 2026.

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