Novel restriction fragment length polymorphisms in the cellular oncogene SEA.

Article

Novel restriction fragment length polymorphisms in the cellular oncogene SEA.

Hematologic pathology - 1 Jan 1992

Koduru P R, Goh J C, Broome J D

Abstract excerpt

The human homologue of the SEA oncogene has been mapped recently to chromosome band 11q13. While studying the possible involvement of this gene in the variant translocation t(9;22;11) (q34;q11;q13) in a case of chronic myelogenous leukemia, we identified novel polymorphisms for XbaI and SacI rest...

Topics

DNA
Deoxyribonucleases, Type II Site-Specific
Gene Frequency
Genotype
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Polymorphism, Restriction Fragment Length
Proto-Oncogenes
Restriction Mapping
Tumor Cells, Cultured

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