Elevated frequency of an ETS-1 restriction fragment polymorphism in chronic B-cell leukaemia.

doi:10.1007/BF00217361

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Article

Elevated frequency of an ETS-1 restriction fragment polymorphism in chronic B-cell leukaemia.

Human genetics - 1 May 1993

Crossen P E, Morrison M J

Abstract excerpt

We studied the frequency of an SstI polymorphism in 70 patients with chronic B-cell leukaemia (CLL) and 100 normal controls. There was a highly significant difference in the distribution of the three genotypes between the CLL patients and the normal controls (chi 2 = 13.46, 2 df, P < 0.001). The...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Chi-Square Distribution
Deoxyribonucleases, Type II Site-Specific
Female
Gene Frequency
Genotype
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Male
Middle Aged
Polymorphism, Restriction Fragment Length
Proto-Oncogenes

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