Isolation and characterization of Actinomyces viscosus mutants defective in binding salivary proline-rich proteins.

doi:10.1128/iai.60.3.1095-1100.1992

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Isolation and characterization of Actinomyces viscosus mutants defective in binding salivary proline-rich proteins.

Infection and immunity - 1 Mar 1992

Nesbitt W E, Beem J E, Leung K P, Clark W B

Abstract excerpt

Recent studies have provided evidence for human salivary proline-rich proteins (PRPs) serving as potential receptors in the acquired pellicle for Actinomyces viscosus type 1 fimbriae. We report here the isolation of mutants derived from A. viscosus T14V-J1 which are defective in binding to PRPs partially purified from parotid gland saliva. Mutagenesis with ethyl methanesulfonate preceded enrichment for cells...

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Isolation and characterization of Actinomyces viscosus mutants defective in binding salivary proline-rich proteins.

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Isolation and characterization of Actinomyces viscosus mutants defective in binding salivary proline-rich proteins.

Abstract excerpt

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