Article
Construction of a novel transposon mutagenesis system useful in the isolation of Streptococcus parasanguis mutants defective in Fap1 glycosylation.
Infection and immunity - 1 Dec 2002
Chen Qiang, Wu Hui, Fives-Taylor Paula M
Abstract excerpt
Streptococcus parasanguis, a primary colonizer of the tooth surface, has long, peritrichous fimbriae. A fimbria-associated protein, Fap1, is identified as an adhesin of S. parasanguis FW213. The mature Fap1 protein is glycosylated, and the glycosylation is required for fimbria biogenesis and bacterial adhesion. Little is known about the mechanism of Fap1 glycosylation due to the lack of identifiable mutants. A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.